Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852643 | 1.00 | CES2 (0.41) | CES2CES1SMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL29117784 | 0.98 | SMN1; SMN2 (0.38) | CES2CES1SMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL29163004 | 0.98 | SMN1; SMN2 (0.38) | CES2CES1SMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL27830024 | 0.86 | SMN1; SMN2 (0.40) | CES2CES1SMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL27582705 | 0.84 | SMN1; SMN2 (0.39) | CES2CES1SMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL2996954 | 0.84 | SMN1; SMN2 (0.39) | CES2CES1SMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL27600012 | 0.84 | SMN1; SMN2 (0.42) | CES2CES1SMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL21722132 | 0.82 | SMN1; SMN2 (0.36) | CES2CES1SMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL29117884 | 0.81 | SMN1; SMN2 (0.40) | CES2CES1SMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL5410841 | 0.81 | SMN1; SMN2 (0.37) | CES2CES1SMN1; SMN2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321101-A | Nitrile group-containing copolymer rubber, rubber composition and rubber crosslinked product | 日本瑞翁株式会社 | 2023-12-29 | — | — | CN | disclosed |
| EP-0429287-A2 | Anti-inflammatory furanone compounds | ALLERGAN, INC. (US) | 1991-05-29 | — | — | EP | disclosed |