Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21722132 | 0.98 | SMN1; SMN2 (0.36) | SMN1; SMN2CES2CES1HDAC8HDAC6 | |
| Acrylic Acid SCHEMBL28288425 | 0.88 | LMNA (0.32) | SMN1; SMN2GRIK1 | |
| SCHEMBL28244777 | 0.85 | ALDH1A1 (0.37) | — | |
| SCHEMBL9852643 | 0.84 | CES2 (0.41) | SMN1; SMN2CES2CES1HDAC8HDAC6 | |
| SCHEMBL9852642 | 0.84 | CES2 (0.41) | SMN1; SMN2CES2CES1HDAC8HDAC6 | |
| SCHEMBL27830024 | 0.82 | SMN1; SMN2 (0.40) | SMN1; SMN2CES2CES1HDAC8HDAC6 | |
| SCHEMBL29163004 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2CES2CES1HDAC8HDAC6 | |
| SCHEMBL29117784 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2CES2CES1HDAC8HDAC6 | |
| SCHEMBL27600012 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2CES2CES1HDAC8HDAC6 | |
| SCHEMBL27582705 | 0.81 | SMN1; SMN2 (0.39) | SMN1; SMN2CES2CES1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009304-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-10-01 | — | — | EP | disclosed |
| EP-2003353-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-8230986-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100184519-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| US-20090173591-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-2009304-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-31 | — | — | EP | disclosed |
| EP-2003353-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-17 | — | — | EP | disclosed |