SCHEMBL9852701

SCHEMBL9852701

C=C1CCOC(c2ccccc2)(c2ccccc2)O1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
CYP1A2 P05177 1/20 0.34
EGFR P00533 2/20 0.33
OPRM1 P35372 4/20 0.32
OPRK1 P41145 4/20 0.32
OPRL1 P41146 4/20 0.32
OPRD1 P41143 2/20 0.31
OGFRL1 Q5TC84 1/20 0.31
MEN1 O00255 1/20 0.31
CYP2C9 P11712 1/20 0.31
KMT2A Q03164 1/20 0.31
CHRNB2 P17787 1/20 0.30
SLC6A2 P23975 1/20 0.30
CHRNB4 P30926 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA4 P43681 1/20 0.30
SLC6A3 Q01959 1/20 0.30
CNR1 P21554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8931208 0.82 EGFR (0.36) HDAC1HDAC2EGFROPRM1OPRK1
SCHEMBL1256099 0.74 CHEK2 (0.39) HDAC1HDAC2CYP1A2OPRM1OPRK1
SCHEMBL27825774 0.72 CHEK2 (0.38) HDAC1HDAC2CYP1A2OPRM1OPRK1
SCHEMBL14778257 0.70 GAA (0.46) CYP1A2MEN1KMT2A
SCHEMBL9618088 0.70 MEN1 (0.46) CYP1A2MEN1KMT2A
SCHEMBL28811509 0.65 ITGB2 (0.37) CYP1A2CHRNB2SLC6A2CHRNB4CHRNA3
SCHEMBL13745023 0.65 OPRM1 (0.37) HDAC1HDAC2OPRM1OPRK1OPRL1
SCHEMBL19443834 0.64 TSHR (0.46)
SCHEMBL14081492 0.64 OPRM1 (0.42) CYP1A2OPRM1OPRK1OPRL1OPRD1
SCHEMBL9792509 0.64 NOTUM (0.39) MEN1KMT2ASLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0425832-A1 Poly(keto-esters) QUANTUM CHEMICAL CORPORATION (US) 1991-05-08 EP disclosed