SCHEMBL8931208

SCHEMBL8931208

C=C1COC(c2ccccc2)(c2ccccc2)O1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.36
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
OPRM1 P35372 1/20 0.31
OPRK1 P41145 1/20 0.31
OPRL1 P41146 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
RECQL P46063 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CFTR P13569 1/20 0.31
GOPC Q9HD26 1/20 0.31
MAOA P21397 2/20 0.30
MAOB P27338 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9852701 0.82 HDAC1 (0.36) EGFRHDAC1HDAC2OPRM1OPRK1
SCHEMBL8754471 0.75 CYP1A2 (0.35) EGFRHDAC1HDAC2OPRM1OPRK1
SCHEMBL1256099 0.69 CHEK2 (0.39) HDAC1HDAC2GRIN1GRIN2AOPRM1
SCHEMBL13745023 0.69 OPRM1 (0.37) HDAC1HDAC2GRIN1GRIN2AOPRM1
SCHEMBL27825774 0.67 CHEK2 (0.38) HDAC1HDAC2GRIN1GRIN2AOPRM1
SCHEMBL9618088 0.65 MEN1 (0.46) GRIN1GRIN2A
SCHEMBL14778257 0.65 GAA (0.46) GRIN1GRIN2A
SCHEMBL23117178 0.65 SIGMAR1 (0.31) MAOAMAOB
SCHEMBL9488195 0.65 OPRM1 (0.36) OPRM1OPRK1OPRL1CFTRGOPC
SCHEMBL1698175 0.65 CA1 (0.37) OPRM1OPRK1OPRL1CFTRGOPC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63277213-A None JP disclosed
US-10919909-B2 Photoinitiated reactions LINTFIELD LIMITED (GB) 2021-02-16 US disclosed
US-20190211031-A1 PHOTOINITIATED REACTIONS LINTFIELD LIMITED (GB) 2019-07-11 US disclosed
US-10221193-B2 Photoinitiated reactions Lintfiled Limited (GB) 2019-03-05 US disclosed
US-20130105297-A1 PHOTOINITIATED REACTIONS LINTFIELD LIMITED (GB) 2013-05-02 US disclosed
US-20130105297-A1 PHOTOINITIATED REACTIONS LINTFIELD LIMITED (GB) 2013-05-02 US disclosed
US-8030368-B2 Photoinitiated reactions LINTFIELD LIMITED (GB) 2011-10-04 US disclosed
US-8030368-B2 Photoinitiated reactions LINTFIELD LIMITED (GB) 2011-10-04 US disclosed
US-7402374-B2 Method for colored image formation FUJIFILM CORPORATION (JP) 2008-07-22 US disclosed
US-7402374-B2 Method for colored image formation FUJIFILM CORPORATION (JP) 2008-07-22 US disclosed
EP-0564601-A1 PROCESS FOR CONVERTING SOLID AND LIQUID POLYKETONES TO POLYESTERS EXXON CHEMICAL PATENTS INC. (US) 1993-10-13 EP disclosed
EP-0536787-A1 Process for converting polyketones to poly(keto-esters) QUANTUM CHEMICAL CORPORATION (US) 1993-04-14 EP disclosed
US-5180797-A Process for converting polyketones to polyesters with organic peroxy acid EXXON CHEMICAL PATENTS INC. (US) 1993-01-19 US disclosed
US-5140080-A Reacting polyketone with aqueous hydrogen peroxide in the presence of a lewis acid and a carboxylic acid QUANTUM CHEMICAL CORPORATION (US) 1992-08-18 US disclosed
WO-1992012193-A1 PROCESS FOR CONVERTING SOLID AND LIQUID POLYKETONES TO POLYESTERS EXXON CHEMICAL PATENTS INC. (US) 1992-07-23 WO disclosed
US-5064932-A Addition-condensation polymers of an alpha-olefin and carbon monoxide oxidized by an organic peroxyacid; photo- and biodegradable plastics QUANTUM CHEMICAL CORPORATION (US) 1991-11-12 US disclosed
EP-0425832-A1 Poly(keto-esters) QUANTUM CHEMICAL CORPORATION (US) 1991-05-08 EP disclosed
US-4957997-A OXIDATION WITH PEROXY ACID QUANTUM CHEMICAL CORPORATION (US) 1990-09-18 US disclosed
US-4929711-A PEROXIDATION WITH PERACIDS QUANTUM CHEMICAL CORPORATION (US) 1990-05-29 US disclosed
JP-S63277213-A NOVEL ETHYLENE COPOLYMER NIPPON PETROCHEM CO LTD 1988-11-15 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919909-B2 Photoinitiated reactions KMO, DECR1, PPOX EGFR 4387/4885HDAC1 4507/4885HDAC2 4579/4885
US-20130105297-A1 PHOTOINITIATED REACTIONS KMO, DECR1, DDT EGFR 4418/4885HDAC1 4515/4885HDAC2 4581/4885
US-10221193-B2 Photoinitiated reactions KMO, DECR1, DDT EGFR 4418/4885HDAC1 4515/4885HDAC2 4581/4885
US-20190211031-A1 PHOTOINITIATED REACTIONS DOHH, PAH, DBH EGFR 4188/4885HDAC1 3932/4885HDAC2 3806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.