Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 8/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6447474 | 0.87 | PKM (0.50) | SMN1; SMN2PKMCTSSHTTCAPN1 | |
| SCHEMBL6447475 | 0.87 | PKM (0.50) | SMN1; SMN2PKMCTSSHTTCAPN1 | |
| SCHEMBL4728438 | 0.84 | MME (0.45) | SMN1; SMN2PKMPOLBGAAMAPT | |
| SCHEMBL5781357 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2PKMCTSSHTTCAPN1 | |
| SCHEMBL7027854 | 0.81 | CTSS (0.69) | SMN1; SMN2PKMCTSSHTTCAPN1 | |
| SCHEMBL6802863 | 0.81 | CTSS (0.69) | SMN1; SMN2PKMCTSSHTTCAPN1 | |
| SCHEMBL5516574 | 0.81 | PKM (0.58) | SMN1; SMN2PKMCTSSHTTCAPN1 | |
| SCHEMBL5516579 | 0.81 | PKM (0.58) | SMN1; SMN2PKMCTSSHTTCAPN1 | |
| SCHEMBL6801263 | 0.81 | CTSS (0.69) | SMN1; SMN2PKMCTSSHTTCAPN1 | |
| SCHEMBL6801412 | 0.81 | HTT (0.56) | SMN1; SMN2PKMCTSSHTTCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417454-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1991-03-20 | — | — | EP | disclosed |