Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1RN | P18510 | 4/20 | 0.56 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.51 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | ECE1 | P42892 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852696 | 0.91 | KISS1R (0.59) | KISS1R | |
| SCHEMBL9852721 | 0.89 | PSMB8 (0.56) | MMP2MMP9MMP8PSMB8CTSS | |
| SCHEMBL11593454 | 0.80 | KISS1R (0.65) | IL1RNERAP2ERAP1KISS1R | |
| SCHEMBL29586130 | 0.80 | ERAP2 (0.68) | IL1RNERAP2ERAP1KISS1R | |
| SCHEMBL31452846 | 0.80 | ERAP2 (0.70) | IL1RNERAP2ERAP1KISS1RECE1 | |
| SCHEMBL5193392 | 0.80 | ALOX15 (0.59) | ERAP2MMP2MMP9MMP8ECE1 | |
| SCHEMBL9630737 | 0.80 | KISS1R (0.57) | KISS1R | |
| SCHEMBL31332432 | 0.80 | IL1RN (0.56) | IL1RNERAP2 | |
| SCHEMBL31430944 | 0.80 | ERAP2 (0.69) | IL1RNERAP2ERAP1ECE1 | |
| SCHEMBL29362362 | 0.80 | ERAP2 (0.69) | IL1RNERAP2ERAP1KISS1RECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328089-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | claimed |
| EP-0417454-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1991-03-20 | — | — | EP | disclosed |
| EP-0328089-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | disclosed |