Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | CPA1 | P15085 | 1/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4954937 | 0.87 | TDP1 (0.58) | PIN1TDP1MEN1KMT2ALMNA | |
| SCHEMBL1514490 | 0.87 | TDP1 (0.58) | PIN1TDP1MEN1KMT2ALMNA | |
| SCHEMBL22129672 | 0.87 | HRH4 (0.57) | PIN1TDP1MEN1KMT2ALMNA | |
| SCHEMBL22129673 | 0.87 | HRH4 (0.57) | PIN1TDP1MEN1KMT2ALMNA | |
| SCHEMBL9632016 | 0.86 | HRH4 (0.47) | PIN1TDP1MMEACECPA1 | |
| SCHEMBL24130549 | 0.86 | PIN1 (0.55) | PIN1TDP1MEN1KMT2ALMNA | |
| SCHEMBL22129667 | 0.86 | PIN1 (0.55) | PIN1TDP1MEN1KMT2ALMNA | |
| SCHEMBL10722504 | 0.86 | PIN1 (0.64) | PIN1TDP1MEN1KMT2ALMNA | |
| SCHEMBL2326317 | 0.84 | PIN1 (0.52) | PIN1TDP1MEN1KMT2ALMNA | |
| SCHEMBL9727776 | 0.83 | HRH4 (0.53) | PIN1MEN1KMT2AMMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417454-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1991-03-20 | — | — | EP | disclosed |
| EP-0328089-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | disclosed |