Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 4/20 | 0.51 |
| ▸ | ACE | P12821 | 6/20 | 0.50 |
| ▸ | MME | P08473 | 5/20 | 0.50 |
| ▸ | CPA1 | P15085 | 3/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18424523 | 0.92 | PIN1 (0.60) | HRH4PIN1LCKACEMME | |
| SCHEMBL18424525 | 0.92 | PIN1 (0.60) | HRH4PIN1LCKACEMME | |
| SCHEMBL10722504 | 0.85 | PIN1 (0.64) | HRH4PIN1LCKACEMME | |
| SCHEMBL9852754 | 0.83 | PIN1 (0.57) | HRH4PIN1ACEMMECPA1 | |
| SCHEMBL24597913 | 0.81 | CHRND (0.51) | HRH4PIN1LCKMMEOPRD1 | |
| SCHEMBL18478935 | 0.78 | ACE (0.60) | ACEMMECPA1ACE2OPRD1 | |
| SCHEMBL18478933 | 0.78 | ACE (0.60) | ACEMMECPA1ACE2OPRD1 | |
| SCHEMBL23955938 | 0.78 | ACE (0.60) | ACEMMECPA1ACE2OPRD1 | |
| SCHEMBL13016862 | 0.78 | OPRD1 (0.53) | LCKOPRD1 | |
| SCHEMBL3659514 | 0.77 | HRH4 (0.64) | HRH4PIN1ACEMMECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140009-A | Stable against proteolytic enzymes; anticarcinogenic agents; urogenital disorders | TAP PHARMACEUTICALS, INC. (US) | 1992-08-18 | — | — | US | disclosed |