Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | NNMT | P40261 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6628270 | 0.86 | PARP10 (0.53) | PARP10PARP1CA1CA2PARP2 | |
| SCHEMBL15881098 | 0.84 | KMT2A (0.41) | PARP10PARP1CA1CA2PARP2 | |
| SCHEMBL21409951 | 0.82 | PLAU (0.44) | SIRT6NNMTMKNK1MKNK2MAP4K4 | |
| SCHEMBL9852805 | 0.81 | PARP10 (0.46) | PARP10ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL28960220 | 0.77 | MEN1 (0.35) | SIRT6NNMTKMT2AMEN1 | |
| SCHEMBL19066140 | 0.75 | KDM4E (0.36) | ALDH1A1NNMTKMT2AMEN1KDM4E | |
| SCHEMBL29178970 | 0.75 | MEN1 (0.34) | NNMTKMT2AMEN1 | |
| SCHEMBL14820284 | 0.75 | PARP1 (0.47) | PARP10PARP1CA1CA2PARP2 | |
| SCHEMBL3825167 | 0.73 | FTO (0.42) | CA1CA2ALDH1A1KMT2AMEN1 | |
| SCHEMBL22250702 | 0.72 | NNMT (0.59) | ALDH1A1SIRT6NNMTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444286-A1 | Sulphonylated pyrimidine carboxylic acid amides | BAYER AG (DE) | 1991-09-04 | — | — | EP | disclosed |