Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 2/20 | 0.35 |
| ▸ | IL1RN | P18510 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | YAP1 | P46937 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98063 | 0.92 | KDM4E (0.41) | KDM4EHDAC1HDAC6CYP19A1CYP11B1 | |
| SCHEMBL2963795 | 0.87 | KDM4E (0.51) | KDM4EHDAC1HDAC6CYP19A1ALDH1A1 | |
| SCHEMBL7097075 | 0.75 | KDM4E (0.50) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL10572726 | 0.71 | KDM4E (0.46) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL98389 | 0.71 | KDM4E (0.46) | KDM4ECYP19A1ALDH1A1HPGDGLA | |
| SCHEMBL10567911 | 0.71 | KDM4E (0.37) | KDM4EALDH1A1CYP1A2GLAGAA | |
| SCHEMBL8919340 | 0.71 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL17543765 | 0.70 | KDM4E (0.45) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL11325430 | 0.69 | PKM (0.43) | PDE4DL3MBTL1MEN1KMT2ACRBN | |
| SCHEMBL97226 | 0.68 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426128-A1 | Carbostyril compound | Otsuka Pharmaceutical Co., Limited (JP) | 2012-03-07 | — | — | EP | disclosed |