Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15950962 | 0.95 | CYP2D6 (0.57) | CYP2D6ALDH1A1KDM4EKMT2ANPSR1 | |
| SCHEMBL16245059 | 0.91 | CYP2D6 (0.55) | CYP2D6ALDH1A1KDM4EKMT2ANPSR1 | |
| SCHEMBL3951270 | 0.89 | CYP2D6 (0.56) | CYP2D6ALDH1A1KDM4EKMT2ANPSR1 | |
| SCHEMBL20595058 | 0.88 | CYP2D6 (0.64) | CYP2D6ALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL25175947 | 0.87 | SMN1; SMN2 (0.56) | CYP2D6ALDH1A1KDM4EKMT2ANPSR1 | |
| SCHEMBL196226 | 0.85 | CYP2D6 (0.67) | CYP2D6ALDH1A1KDM4EKMT2ANPSR1 | |
| SCHEMBL7944945 | 0.85 | CYP2D6 (0.67) | CYP2D6ALDH1A1KDM4EKMT2ANPSR1 | |
| SCHEMBL184777 | 0.85 | CYP2D6 (0.60) | CYP2D6KMT2ATP53MEN1 | |
| SCHEMBL21597017 | 0.84 | CYP2D6 (0.50) | CYP2D6ALDH1A1KDM4EKMT2ANPSR1 | |
| SCHEMBL10385453 | 0.83 | ALDH1A1 (0.58) | ALDH1A1KDM4EKMT2ANPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441226-A1 | (cyanomethyl)pyridines useful as PAF antagonists | J. URIACH & CIA. S.A. (ES) | 1991-08-14 | — | — | EP | disclosed |