Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146771 | 0.85 | MTNR1A (0.55) | MTNR1AMTNR1BEPHX1ACP3CYP19A1 | |
| Hydrochloric Acid SCHEMBL30185866 | 0.83 | MTNR1A (0.53) | MTNR1AMTNR1BEPHX1ACP3CYP19A1 | |
| SCHEMBL28696042 | 0.83 | MTNR1A (0.53) | MTNR1AMTNR1BEPHX1ACP3CYP19A1 | |
| SCHEMBL4275218 | 0.83 | GABBR2 (0.46) | CYP1A2PKM | |
| SCHEMBL2097829 | 0.83 | MTNR1A (0.50) | MTNR1AMTNR1BEPHX1ACP3CYP19A1 | |
| SCHEMBL7192033 | 0.79 | MTNR1A (0.50) | MTNR1AMTNR1BEPHX1ACP3CYP19A1 | |
| SCHEMBL9179418 | 0.77 | MTNR1A (0.49) | MTNR1AMTNR1BEPHX1ACP3CYP19A1 | |
| SCHEMBL8810284 | 0.77 | GABBR2 (0.53) | MTNR1AMTNR1BEPHX1CYP19A1SLC6A2 | |
| SCHEMBL1541691 | 0.77 | GABBR2 (0.53) | MTNR1AMTNR1BEPHX1CYP19A1SLC6A2 | |
| SCHEMBL6940539 | 0.77 | CYP19A1 (0.50) | MTNR1AMTNR1BEPHX1ACP3CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441226-A1 | (cyanomethyl)pyridines useful as PAF antagonists | J. URIACH & CIA. S.A. (ES) | 1991-08-14 | — | — | EP | disclosed |