Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36752 | 0.83 | — | — | |
| Water SCHEMBL28139555 | 0.81 | — | — | |
| SCHEMBL19665080 | 0.79 | SMN1; SMN2 (0.46) | HCAR2SMN1; SMN2NPC1RAB9ALMNA | |
| Acetic Acid SCHEMBL27320957 | 0.78 | HCAR2 (0.53) | HCAR2SMN1; SMN2NPC1RAB9ALMNA | |
| Acrylic Acid SCHEMBL28733327 | 0.78 | HCAR2 (0.58) | HCAR2SMN1; SMN2NPC1RAB9ALMNA | |
| Acetic Acid SCHEMBL27304195 | 0.75 | HCAR2 (0.46) | HCAR2SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL31038228 | 0.74 | SMN1; SMN2 (0.44) | HCAR2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| Phenol SCHEMBL27636726 | 0.74 | ABCG2 (0.45) | HCAR2SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL9853217 | 0.73 | HCAR2 (0.40) | HCAR2SMN1; SMN2NPC1RAB9ALMNA | |
| Furan SCHEMBL28876944 | 0.72 | RAB9A (0.43) | HCAR2SMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413293-A2 | 1-(Benzo[b]thienyl)-2-(thienyl) ethenes and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-02-20 | — | — | EP | disclosed |