Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36752 | 0.75 | — | — | |
| Acrylic Acid SCHEMBL28733327 | 0.74 | HCAR2 (0.58) | HCAR2MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2054031 | 0.73 | — | — | |
| SCHEMBL9853161 | 0.73 | HCAR2 (0.43) | HCAR2MAPTHPGDALDH1A1LMNA | |
| SCHEMBL19665080 | 0.72 | SMN1; SMN2 (0.46) | HCAR2MAPTHPGDALDH1A1LMNA | |
| SCHEMBL9853212 | 0.70 | HCAR2 (0.57) | HCAR2MAPTHPGDALDH1A1LMNA | |
| SCHEMBL31038228 | 0.67 | SMN1; SMN2 (0.44) | HCAR2MAPTHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7034994 | 0.67 | SLC6A2 (0.35) | HCAR2MAPTHPGDALDH1A1SLC6A2 | |
| Furan SCHEMBL28876944 | 0.65 | RAB9A (0.43) | HCAR2MAPTHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL8475626 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413293-A2 | 1-(Benzo[b]thienyl)-2-(thienyl) ethenes and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-02-20 | — | — | EP | disclosed |
| US-4904674-A | FREE OF AGGLOMERATION OF FIBRILLATION | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-02-27 | — | — | US | disclosed |