Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.60 |
| ▸ | ANPEP | P15144 | 2/20 | 0.57 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.57 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.57 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | XIAP | P98170 | 1/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.53 |
| ▸ | CTSC | P53634 | 1/20 | 0.52 |
| ▸ | LAP3 | P28838 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1041526 | 1.00 | MMP2 (0.60) | MMP2ANPEPRNPEPDNPEPALPI | |
| SCHEMBL24346075 | 1.00 | MMP2 (0.60) | MMP2ANPEPRNPEPDNPEPALPI | |
| Hydrochloric Acid SCHEMBL9556981 | 0.98 | MMP2 (0.58) | MMP2ANPEPRNPEPDNPEPALPI | |
| SCHEMBL6013478 | 0.90 | MMP2 (0.60) | MMP2ANPEPRNPEPDNPEPALPI | |
| SCHEMBL6013477 | 0.90 | MMP2 (0.60) | MMP2ANPEPRNPEPDNPEPALPI | |
| SCHEMBL3161775 | 0.88 | MMP2 (0.57) | MMP2ANPEPRNPEPDNPEPALPI | |
| SCHEMBL23641829 | 0.85 | MMP2 (0.61) | MMP2ANPEPRNPEPDNPEPALPI | |
| SCHEMBL3210919 | 0.84 | ANPEP (0.74) | ANPEPRNPEPDNPEPALPIPKM | |
| SCHEMBL3210913 | 0.84 | ANPEP (0.74) | ANPEPRNPEPDNPEPALPIPKM | |
| SCHEMBL7299909 | 0.84 | ANPEP (0.74) | ANPEPRNPEPDNPEPALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412350-A2 | Renininhibitors, procedure for their preparation and use as medicaments | BAYER AG (DE) | 1991-02-13 | — | — | EP | disclosed |