Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MME | P08473 | 2/20 | 0.53 |
| ▸ | ANPEP | P15144 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | TACR1 | P25103 | 3/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9557063 | 0.99 | POLB (0.54) | POLBMMEANPEPCTSLTACR1 | |
| SCHEMBL12293296 | 0.90 | MME (0.44) | POLBMMEANPEPCTSLECE1 | |
| SCHEMBL7298200 | 0.90 | SLC15A1 (0.55) | POLBMMEANPEPCTSLTACR1 | |
| SCHEMBL8673841 | 0.89 | TACR1 (0.59) | POLBMMEANPEPCTSLTACR1 | |
| SCHEMBL28490041 | 0.89 | TACR1 (0.59) | POLBMMEANPEPCTSLTACR1 | |
| SCHEMBL10742278 | 0.88 | ALDH1A1 (0.62) | POLBANPEPALDH1A1THRBCYP2C9 | |
| SCHEMBL6064582 | 0.88 | ALDH1A1 (0.62) | POLBANPEPALDH1A1THRBCYP2C9 | |
| Bromide SCHEMBL8668104 | 0.88 | TACR1 (0.57) | POLBMMEANPEPCTSLTACR1 | |
| Hydrochloric Acid SCHEMBL10359241 | 0.87 | ALDH1A1 (0.61) | POLBANPEPALDH1A1THRBCYP2C9 | |
| Bromide SCHEMBL10742850 | 0.87 | ALDH1A1 (0.61) | POLBANPEPALDH1A1THRBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412350-A2 | Renininhibitors, procedure for their preparation and use as medicaments | BAYER AG (DE) | 1991-02-13 | — | — | EP | disclosed |