Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853370 | 1.00 | TSHR (0.52) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| SCHEMBL7727586 | 1.00 | TSHR (0.52) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| SCHEMBL9853372 | 1.00 | TSHR (0.52) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| SCHEMBL4988977 | 0.97 | TSHR (0.48) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| SCHEMBL10885356 | 0.92 | — | — | |
| SCHEMBL8078444 | 0.83 | KMT2A (0.50) | TSHRALDH1A1ALOX15KMT2AKDM4E | |
| SCHEMBL2162531 | 0.80 | — | — | |
| SCHEMBL18092234 | 0.80 | KMT2A (0.64) | ALDH1A1ALOX15KMT2A | |
| SCHEMBL8626072 | 0.80 | KMT2A (0.64) | ALDH1A1ALOX15KMT2A | |
| SCHEMBL1819963 | 0.80 | KMT2A (0.64) | ALDH1A1ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423874-A2 | Process for the preparation of aldehydes | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-04-24 | — | — | EP | disclosed |