Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853370 | 0.97 | TSHR (0.52) | TSHRHIF1AALDH1A1FAAHTRPV1 | |
| SCHEMBL7727586 | 0.97 | TSHR (0.52) | TSHRHIF1AALDH1A1FAAHTRPV1 | |
| SCHEMBL9853372 | 0.97 | TSHR (0.52) | TSHRHIF1AALDH1A1FAAHTRPV1 | |
| SCHEMBL9853373 | 0.97 | TSHR (0.52) | TSHRHIF1AALDH1A1FAAHTRPV1 | |
| SCHEMBL10885356 | 0.94 | — | — | |
| SCHEMBL8078444 | 0.85 | KMT2A (0.50) | TSHRALDH1A1ALOX15KMT2AKDM4E | |
| SCHEMBL2162531 | 0.82 | — | — | |
| SCHEMBL18092234 | 0.82 | KMT2A (0.64) | ALDH1A1ALOX15KMT2A | |
| SCHEMBL8626072 | 0.82 | KMT2A (0.64) | ALDH1A1ALOX15KMT2A | |
| SCHEMBL8626074 | 0.82 | KMT2A (0.64) | ALDH1A1ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9403854-B2 | Cross-metathesis reaction of functionalized and substituted olefins using group 8 transition metal carbene complexes as metathesis catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-08-02 | — | — | US | disclosed |
| US-20160159934-A1 | USES OF CERTAIN PLATINOID ACCUMULATING PLANTS FOR USE IN ORGANIC CHEMICAL REACTIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 2016-06-09 | — | — | US | disclosed |
| US-20160159934-A1 | USES OF CERTAIN PLATINOID ACCUMULATING PLANTS FOR USE IN ORGANIC CHEMICAL REACTIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 2016-06-09 | — | — | US | disclosed |
| EP-1489072-B1 | PROCESS FOR ASYMMETRIC INTRAMOLECULAR (3+2) CYCLO-ADDITION OF HYDRAZONES | JAPAN SCIENCE & TECH AGENCY (JP) | 2016-01-20 | — | — | EP | disclosed |
| US-20140288319-A1 | CROSS-METATHESIS REACTION OF FUNCTIONALIZED AND SUBSTITUTED OLEFINS USING GROUP 8 TRANSITION METAL CARBENE COMPLEXES AS METATHESIS CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-09-25 | — | — | US | disclosed |
| WO-2012074547-A2 | STEROID COMPOUNDS AS RORγt MODULATORS AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2012-06-07 | — | — | WO | disclosed |
| US-7351831-B2 | Process for asymmetric intramolecular [3+2] cyclo-addition of hydrazones | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-04-01 | — | — | US | disclosed |
| US-20070155975-A1 | Cross-metathesis reaction of functionalized and substituted olefins using group 8 transition metal carbene complexes as metathesis catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-07-05 | — | — | US | disclosed |
| US-20050165237-A1 | Process for asymmetric intramolecular [3+2] cyclo-addition of hydrazones | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2005-07-28 | — | — | US | disclosed |
| EP-1489072-A1 | PROCESS FOR ASYMMETRIC INTRAMOLECULAR (3+2) CYCLO-ADDITION OF HYDRAZONES | Japan Science and Technology Agency (JP) | 2004-12-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288319-A1 | CROSS-METATHESIS REACTION OF FUNCTIONALIZED AND SUBSTITUTED OLEFINS USING GROUP 8 TRANSITION METAL CARBENE COMPLEXES AS METATHESIS CATALYSTS | OXER1, OSTC, OXSR1 | TSHR 2555/4885HIF1A 3949/4885ALDH1A1 1898/4885 |
| US-20070155975-A1 | Cross-metathesis reaction of functionalized and substituted olefins using group 8 transition metal carbene complexes as metathesis catalysts | OXER1, OSTC, OXSR1 | TSHR 2555/4885HIF1A 3949/4885ALDH1A1 1898/4885 |
| US-20050165237-A1 | Process for asymmetric intramolecular [3+2] cyclo-addition of hydrazones | HRH2, H1-2, HRH1 | TSHR 2055/4885HIF1A 1586/4885ALDH1A1 2408/4885 |
| US-20160159934-A1 | USES OF CERTAIN PLATINOID ACCUMULATING PLANTS FOR USE IN ORGANIC CHEMICAL REACTIONS | OAT, PPA1, ITPA | TSHR 4224/4885HIF1A 1848/4885ALDH1A1 1264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.