Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.57 |
| ▸ | SQLE | Q14534 | 4/20 | 0.57 |
| ▸ | FNTA | P49354 | 1/20 | 0.53 |
| ▸ | FNTB | P49356 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626074 | 1.00 | KMT2A (0.64) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL18092234 | 1.00 | KMT2A (0.64) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL8626072 | 1.00 | KMT2A (0.64) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL9189400 | 0.90 | KMT2A (0.68) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL9189396 | 0.90 | KMT2A (0.68) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL24092723 | 0.87 | KMT2A (0.77) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL18705403 | 0.87 | KMT2A (0.77) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL9138262 | 0.87 | KMT2A (0.77) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL9159020 | 0.87 | KMT2A (0.77) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL9137864 | 0.87 | KMT2A (0.77) | KMT2AMAPTALDH1A1MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10150722-B2 | Aldehyde compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2018-12-11 | — | — | US | disclosed |
| EP-3072876-B1 | ALDEHYDE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INT FLAVORS & FRAGRANCES INC (US) | 2018-10-10 | — | — | EP | disclosed |
| US-20180057436-A1 | NOVEL ALDEHYDE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2018-03-01 | — | — | US | disclosed |
| US-9850191-B2 | Aldehyde compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2017-12-26 | — | — | US | disclosed |
| US-20160281027-A1 | NOVEL ALDEHYDE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2016-09-29 | — | — | US | disclosed |
| EP-3072876-A1 | ALDEHYDE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | Closson, Adam P. (US) | 2016-09-28 | — | — | EP | disclosed |
| US-8389466-B2 | Use of carboxylic acid esters as a fragrance substance | SYMRISE AG (DE) | 2013-03-05 | — | — | US | disclosed |
| US-20110104092-A1 | USE OF CARBOXYLIC ACID ESTERS AS A FRAGRANCE SUBSTANCE | SYMRISE AG (DE) | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180057436-A1 | NOVEL ALDEHYDE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | ALDH1A1, TRPA1, ALDH2 | KMT2A 1949/4885MAPT 1742/4885ALDH1A1 1/4885 |
| US-10150722-B2 | Aldehyde compounds and their use in perfume compositions | ALDH1A1, ALDH2, ADH5 | KMT2A 1421/4885MAPT 1342/4885ALDH1A1 1/4885 |
| US-20110104092-A1 | USE OF CARBOXYLIC ACID ESTERS AS A FRAGRANCE SUBSTANCE | FASN, ELOVL5, ALDH16A1 | KMT2A 1635/4885MAPT 1790/4885ALDH1A1 9/4885 |
| US-20160281027-A1 | NOVEL ALDEHYDE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | ALDH1A1, TRPA1, ALDH2 | KMT2A 1949/4885MAPT 1742/4885ALDH1A1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.