Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1315514 | 0.82 | PDE10A (0.56) | PDE10AALDH1A1HPGDGLAMAPT | |
| SCHEMBL3430716 | 0.81 | ADORA2A (0.50) | PDE10AALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL11347425 | 0.80 | ALDH1A1 (0.38) | PDE10AALDH1A1HPGDGLAMAPT | |
| SCHEMBL8594953 | 0.76 | ALDH1A1 (0.48) | PDE10AALDH1A1HPGDGLAMAPT | |
| SCHEMBL15722176 | 0.74 | ALDH1A1 (0.51) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL4418027 | 0.74 | ALDH1A1 (0.46) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL4418030 | 0.74 | ALDH1A1 (0.46) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL6261668 | 0.74 | KMT2A (0.50) | PDE10AALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL18852048 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HPGDGLAMAPTKDM4E | |
| SCHEMBL3359420 | 0.73 | PSMB5 (0.65) | PDE10AALDH1A1HPGDGLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507896-B2 | Compounds having electroluminescent or electron transport properties | MERCK PATENT GMBH (DE) | 2013-08-13 | — | — | US | claimed |
| EP-2250151-A1 | COMPOUNDS HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES | Merck Patent GmbH (DE) | 2010-11-17 | — | — | EP | claimed |
| WO-2009112854-A1 | COMPOUNDS HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES | MERCK PATENT GMBH (DE) | 2009-09-17 | — | — | WO | claimed |
| EP-2641923-B1 | (Co)-polymeric and hybrid (co)-polymeric electron acceptors for organic photovoltaic cell applications | UNIV OF PATRAS (GR) | 2017-05-24 | — | — | EP | disclosed |
| EP-2641923-A1 | (Co)-polymeric and hybrid (co)-polymeric electron acceptors for organic photovoltaic cell applications | University Of Patras (GR) | 2013-09-25 | — | — | EP | disclosed |
| US-8507896-B2 | Compounds having electroluminescent or electron transport properties | MERCK PATENT GMBH (DE) | 2013-08-13 | — | — | US | disclosed |
| US-20110006295-A1 | COMPOUNDS HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES | MERCK PATENT GMBH | 2011-01-13 | — | — | US | disclosed |
| WO-2009149860-A2 | METHOD OF MAKING AN OLED | MERCK PATENT GMBH (DE) | 2009-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110006295-A1 | COMPOUNDS HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES | NR2E3, NR4A2, NR4A3 | PDE10A 4069/4885ALDH1A1 420/4885HPGD 2872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.