Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL985339 | 0.81 | PDE10A (0.56) | PDE10AMAPTTDP1RAB9ASMN1; SMN2 | |
| SCHEMBL30462969 | 0.79 | ADORA2A (0.53) | ADORA2APDE10AMAPTTDP1RAB9A | |
| SCHEMBL3430717 | 0.78 | MAPT (0.46) | ADORA2APDE10AMAPTTDP1RAB9A | |
| SCHEMBL7690919 | 0.78 | L3MBTL1 (0.61) | ADORA2APDE10AMAPTTDP1RAB9A | |
| SCHEMBL30486858 | 0.77 | ADORA2A (0.54) | ADORA2APDE10AMAPTTDP1RAB9A | |
| SCHEMBL29207046 | 0.77 | ADORA2A (0.54) | ADORA2APDE10AMAPTTDP1RAB9A | |
| SCHEMBL29207037 | 0.76 | KDM4E (0.50) | ADORA2APDE10AMAPTTDP1RAB9A | |
| SCHEMBL28815572 | 0.74 | ADORA2A (0.61) | ADORA2APDE10AMAPTTDP1RAB9A | |
| SCHEMBL895785 | 0.73 | ALDH1A1 (0.49) | MAPTTDP1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28280657 | 0.72 | ADORA2A (0.52) | ADORA2APDE10AMAPTTDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2147913-A1 | Styrylquinolines, their process of preparation and their therapeutic uses | BioAlliance Pharma (FR) | 2010-01-27 | — | — | EP | claimed |
| EP-2147913-A1 | Styrylquinolines, their process of preparation and their therapeutic uses | BioAlliance Pharma (FR) | 2010-01-27 | — | — | EP | disclosed |