Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | ARG1 | P05089 | 1/20 | 0.31 |
| ▸ | ARG2 | P78540 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28535462 | 0.80 | DGAT1 (0.44) | DGAT1 | |
| SCHEMBL27482953 | 0.76 | DGAT1 (0.44) | DGAT1 | |
| SCHEMBL20747614 | 0.75 | CA12 (0.33) | MAPT | |
| SCHEMBL20747710 | 0.75 | CA12 (0.33) | MAPT | |
| SCHEMBL2976274 | 0.74 | PRKCA (0.44) | MAPT | |
| SCHEMBL2980891 | 0.74 | PRKCA (0.44) | MAPT | |
| SCHEMBL2479166 | 0.74 | PRKCA (0.44) | MAPT | |
| SCHEMBL3371032 | 0.73 | MAPT (0.35) | MAPT | |
| SCHEMBL6538749 | 0.72 | DGAT1 (0.36) | CTSKDGAT1 | |
| SCHEMBL3370002 | 0.72 | MAPT (0.34) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417803-A1 | [N-(gamma-glutamyl)glycyl] alanine derivatives | SANDOZ LTD. (CH) | 1991-03-20 | — | — | EP | disclosed |