Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 11/20 | 0.35 |
| ▸ | CTSS | P25774 | 7/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853432 | 0.76 | PTPRB (0.44) | MAPTCTSKSMN1; SMN2CA1CA7 | |
| SCHEMBL9306468 | 0.74 | ALDH1A1 (0.32) | MAPTGAAKDM4E | |
| SCHEMBL5779132 | 0.72 | POLB (0.37) | MAPTCTSKCTSSSMN1; SMN2 | |
| SCHEMBL5806972 | 0.72 | ALDH1A1 (0.32) | MAPTGAAKDM4E | |
| SCHEMBL866121 | 0.72 | PKM (0.36) | MAPTMEN1KMT2AKDM4E | |
| SCHEMBL17579881 | 0.71 | PTPRB (0.40) | MAPTCTSKGAA | |
| SCHEMBL17580349 | 0.71 | AAK1 (0.37) | CTSKCTSSSMN1; SMN2CTSB | |
| SCHEMBL17579914 | 0.71 | PTPRB (0.34) | CTSKCTSL | |
| SCHEMBL31252175 | 0.70 | MAPT (0.39) | MAPTCTSKCTSSSMN1; SMN2CTSL | |
| SCHEMBL1433275 | 0.70 | MAPT (0.40) | MAPTCTSKCTSSSMN1; SMN2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417803-A1 | [N-(gamma-glutamyl)glycyl] alanine derivatives | SANDOZ LTD. (CH) | 1991-03-20 | — | — | EP | disclosed |