Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9298903 | 0.91 | SRC (0.47) | SRCTGFBR1ELANEMAPTCYP1A2 | |
| SCHEMBL9853445 | 0.81 | MAPT (0.41) | SRCTGFBR1ELANEMAPTCYP1A2 | |
| SCHEMBL27968879 | 0.78 | MAPT (0.51) | SRCTGFBR1ELANEMAPTMEN1 | |
| SCHEMBL9853726 | 0.76 | KMT2A (0.50) | SRCTGFBR1ELANEMAPTCYP1A2 | |
| SCHEMBL9859625 | 0.76 | ELANE (0.55) | SRCTGFBR1ELANEMAPTGAA | |
| SCHEMBL9298733 | 0.75 | PTGDR2 (0.52) | SRCTGFBR1ELANEMAPTCYP1A2 | |
| SCHEMBL9853454 | 0.75 | MAPT (0.39) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL28667538 | 0.72 | SRC (0.42) | SRCTGFBR1ELANEMAPTGAA | |
| SCHEMBL27907200 | 0.72 | ELANE (0.44) | SRCTGFBR1ELANEMAPTMEN1 | |
| SCHEMBL9282306 | 0.72 | ELANE (0.61) | SRCTGFBR1ELANEMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446718-A2 | Phenoxy bis-maleimides and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | claimed |
| EP-0446718-A2 | Phenoxy bis-maleimides and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | disclosed |