Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9297643 | 0.91 | MAPT (0.49) | MAPTPOLBMAPK1F10GAA | |
| SCHEMBL9853451 | 0.81 | SRC (0.41) | MAPTMAPK1GAAELANESRC | |
| SCHEMBL10897162 | 0.79 | ALDH1A1 (0.51) | MAPTPOLBMAPK1ELANESRC | |
| SCHEMBL28940516 | 0.79 | KDM4E (0.51) | POLBF10GAACTNNB1PYGL | |
| SCHEMBL9860244 | 0.78 | MAPT (0.51) | MAPTPOLBMAPK1ELANESRC | |
| SCHEMBL28338529 | 0.77 | MAPK1 (0.50) | MAPTPOLBMAPK1F10GAA | |
| SCHEMBL9853728 | 0.77 | LMNA (0.50) | MAPTPOLBMAPK1GAAELANE | |
| SCHEMBL28535291 | 0.75 | MAPT (0.50) | MAPTPOLBMAPK1F10GAA | |
| SCHEMBL29555994 | 0.75 | MAPT (0.50) | MAPTPOLBMAPK1F10GAA | |
| SCHEMBL28338598 | 0.74 | MAPT (0.49) | MAPTPOLBMAPK1F10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446718-A2 | Phenoxy bis-maleimides and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | disclosed |