Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 2/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9859625 | 0.85 | ELANE (0.55) | GAASRCTGFBR1ELANEMAPT | |
| SCHEMBL9298733 | 0.84 | PTGDR2 (0.52) | KMT2AMEN1SRCTGFBR1ELANE | |
| SCHEMBL9298903 | 0.84 | SRC (0.47) | KMT2AGAAMEN1SRCTGFBR1 | |
| SCHEMBL9282306 | 0.81 | ELANE (0.61) | GAASRCTGFBR1ELANEMAPT | |
| SCHEMBL2872132 | 0.81 | AKR1C3 (0.48) | KMT2AGAAMEN1USP2KEAP1 | |
| SCHEMBL2879416 | 0.81 | KMT2A (0.48) | KMT2AGAAMEN1USP2KEAP1 | |
| SCHEMBL29963348 | 0.78 | MEN1 (0.68) | KMT2AGAAMEN1USP2KEAP1 | |
| SCHEMBL9857539 | 0.78 | MEN1 (0.68) | KMT2AGAAMEN1USP2KEAP1 | |
| SCHEMBL8375486 | 0.78 | MEN1 (0.47) | KMT2AMEN1MAPTCYP1A2SLC6A2 | |
| SCHEMBL10697260 | 0.77 | CTNNB1 (0.53) | KMT2AGAAMEN1USP2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446722-A1 | Novel hydroxylated phenoxy compounds and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | claimed |
| EP-0446722-A1 | Novel hydroxylated phenoxy compounds and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | disclosed |