Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853457 | 0.77 | MAPT (0.31) | MAPT | |
| SCHEMBL16771549 | 0.77 | NPSR1 (0.33) | LMNATSHRNPSR1MAPTHRH3 | |
| SCHEMBL9853470 | 0.75 | EPHX1 (0.30) | MAPT | |
| SCHEMBL25555185 | 0.74 | TSHR (0.33) | TSHR | |
| SCHEMBL24894338 | 0.72 | ATM (0.31) | — | |
| SCHEMBL20221547 | 0.72 | NPSR1 (0.34) | LMNANPSR1MAPT | |
| SCHEMBL29239801 | 0.72 | OPRM1 (0.35) | LMNA | |
| SCHEMBL4179515 | 0.69 | SLC6A9 (0.36) | NPSR1MAPT | |
| SCHEMBL4876100 | 0.69 | NPSR1 (0.32) | TSHRNPSR1MAPT | |
| SCHEMBL2125006 | 0.68 | NPSR1 (0.32) | NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431605-A2 | 1-Azabicyclo[m.n.O]alkane derivatives, their salts and process for preparing them | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1991-06-12 | — | — | EP | disclosed |