Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2074815 | 0.88 | SCN9A (0.38) | KCNN4 | |
| SCHEMBL2074816 | 0.88 | SCN9A (0.38) | KCNN4 | |
| SCHEMBL985129 | 0.85 | KCNN4 (0.42) | KCNN4 | |
| SCHEMBL4412463 | 0.81 | KCNN4 (0.39) | KCNN4MAPK1 | |
| SCHEMBL985675 | 0.76 | CCNT1 (0.37) | KCNN4 | |
| SCHEMBL985145 | 0.75 | PDE4B (0.43) | KCNN4MAPK1 | |
| SCHEMBL985146 | 0.75 | PDE4B (0.43) | KCNN4MAPK1 | |
| SCHEMBL986040 | 0.75 | KCNN4 (0.40) | KCNN4MAPK1 | |
| SCHEMBL987228 | 0.74 | KCNN4 (0.35) | KCNN4 | |
| SCHEMBL13593420 | 0.74 | KCNN4 (0.49) | KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7872031-B2 | c-MET protein kinase inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-01-18 | — | — | US | claimed |