Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.74 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.66 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851373 | 0.94 | AGTR1 (0.75) | PPARGAGTR1AGTR2 | |
| SCHEMBL8790245 | 0.85 | PPARG (0.68) | PPARGAGTR1AGTR2 | |
| SCHEMBL8396958 | 0.85 | PPARG (1.00) | PPARGAGTR1AGTR2 | |
| SCHEMBL9411713 | 0.84 | PPARG (0.73) | PPARG | |
| SCHEMBL8972114 | 0.84 | PPARG (0.73) | PPARGAGTR1AGTR2 | |
| SCHEMBL8789543 | 0.84 | PPARG (0.64) | PPARGAGTR1AGTR2 | |
| SCHEMBL7850720 | 0.84 | AGTR1 (0.62) | PPARGAGTR1AGTR2 | |
| SCHEMBL9700605 | 0.82 | PPARG (0.73) | PPARGAGTR1AGTR2 | |
| SCHEMBL683752 | 0.82 | AGTR1 (0.81) | PPARGAGTR1AGTR2 | |
| SCHEMBL9853645 | 0.82 | AGTR1 (0.71) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415886-A2 | Aza compounds | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | claimed |
| EP-0415886-A2 | Aza compounds | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | disclosed |