Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KRAS | P01116 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566027 | 0.87 | KDM4C (0.52) | KDM4CPOLBKMT2AGSK3BPARP1 | |
| SCHEMBL12092412 | 0.83 | DDAH1 (0.59) | KDM4CPDE5AKRASKDM4ESMN1; SMN2 | |
| SCHEMBL10650966 | 0.83 | POLB (0.51) | KDM4CPOLBKMT2AKDM4EGSK3B | |
| SCHEMBL9705784 | 0.79 | KDM4C (0.51) | KDM4CGSK3BPARP1 | |
| SCHEMBL379648 | 0.78 | POLB (0.79) | POLBSMN1; SMN2PARP1 | |
| Hydrochloric Acid SCHEMBL28131464 | 0.77 | POLB (0.77) | POLBPARP1PKM | |
| Benzene SCHEMBL28277475 | 0.77 | POLB (0.77) | POLBPARP1 | |
| SCHEMBL9851482 | 0.77 | KDM4C (0.63) | KDM4CPOLBKMT2AKDM4E | |
| Fluoride SCHEMBL28138824 | 0.77 | POLB (0.77) | POLBSMN1; SMN2PARP1 | |
| SCHEMBL588512 | 0.76 | KRAS (0.51) | PDE5AKRASKDM4ESMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415886-A2 | Aza compounds | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | disclosed |