Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972048 | 0.94 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9851500 | 0.91 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9853659 | 0.90 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9851484 | 0.90 | AGTR1 (0.56) | AGTR1AGTR2PDE4APDE4BPDE4C | |
| SCHEMBL9844120 | 0.89 | PDE4A (0.65) | AGTR1AGTR2PDE4APDE4BPDE4C | |
| SCHEMBL9851473 | 0.89 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9853638 | 0.88 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL8393351 | 0.88 | AGTR1 (0.70) | AGTR1AGTR2 | |
| SCHEMBL29486817 | 0.86 | AGTR1 (0.72) | AGTR1AGTR2 | |
| SCHEMBL7622112 | 0.86 | AGTR1 (0.72) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415886-A2 | Aza compounds | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | claimed |
| EP-0426021-A1 | Condensed imidazole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |
| EP-0415886-A2 | Aza compounds | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | disclosed |