Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8378010 | 0.82 | AR (0.50) | ARPTGS2ESR2ALDH1A1HPGD | |
| SCHEMBL17716501 | 0.82 | AR (0.47) | ARESR2L3MBTL1ALDH1A1ESR1 | |
| SCHEMBL9859902 | 0.81 | NCOA1 (0.53) | NCOA1NCOA3SCN9AARBRD4 | |
| SCHEMBL9298242 | 0.81 | NCOA1 (0.61) | NCOA1NCOA3SCN9AARBRD4 | |
| SCHEMBL28336726 | 0.81 | NCOA1 (0.61) | NCOA1NCOA3ARBRD4PTGS2 | |
| SCHEMBL28336683 | 0.78 | NCOA1 (0.61) | NCOA1NCOA3ARBRD4PTGS2 | |
| SCHEMBL4101422 | 0.78 | LTA4H (0.54) | ESR2L3MBTL1ESR1 | |
| SCHEMBL11821093 | 0.78 | NCOA1 (0.56) | NCOA1NCOA3SCN9AARBRD4 | |
| SCHEMBL1096473 | 0.76 | NCOA1 (0.68) | NCOA1NCOA3ARBRD4PTGS2 | |
| SCHEMBL7035775 | 0.76 | NCOA1 (0.53) | NCOA1NCOA3SCN9AARBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446722-A1 | Novel hydroxylated phenoxy compounds and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | disclosed |