SCHEMBL4101422

SCHEMBL4101422

Cc1cc(Oc2ccccc2)ccc1O

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.54
NR1H2 P55055 1/20 0.54
BAX Q07812 1/20 0.54
TSHR P16473 1/20 0.48
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
TDP1 Q9NUW8 2/20 0.45
TP53 P04637 1/20 0.45
AKR1C3 P42330 1/20 0.44
MAOB P27338 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MAOA P21397 1/20 0.43
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43
HSP90AA1 P07900 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23519853 0.90 ALDH1A1 (0.47) ESR1ESR2TDP1TP53MEN1
SCHEMBL30058647 0.89 TP53 (0.54) ESR1ESR2TDP1TP53L3MBTL1
SCHEMBL135848 0.89 TP53 (0.54) ESR1ESR2TDP1TP53L3MBTL1
SCHEMBL9623629 0.86 ESR1 (0.58) LTA4HNR1H2BAXESR1ESR2
SCHEMBL29256758 0.84 LTA4H (0.59) LTA4HNR1H2BAXTSHRESR1
SCHEMBL14363506 0.83 ALOX5 (0.50) LTA4HNR1H2BAXESR1ESR2
SCHEMBL24413594 0.82 PARP15 (0.53) AKR1C3CA1CA2L3MBTL1RAB9A
SCHEMBL10334623 0.82 ESR2 (0.57) TSHRESR2TDP1TP53L3MBTL1
SCHEMBL923019 0.82 TP53 (0.46) LTA4HTSHRESR1ESR2TDP1
SCHEMBL17716506 0.82 TP53 (0.46) ESR1ESR2TDP1TP53CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0446722-A1 Novel hydroxylated phenoxy compounds and process for their preparation Bromine Compounds Ltd. (IL) 1991-09-18 EP claimed
US-20240410055-A1 METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS MERCK PATENT GMBH (DE) 2024-12-12 US disclosed
CN-118076767-A Method and formulation for producing an optical metal oxide layer 默克专利有限公司 2024-05-24 CN disclosed
WO-2023057401-A1 METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS MERCK PATENT GMBH (DE) 2023-04-13 WO disclosed
WO-2022081842-A1 SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER THE BROAD INSTITUTE, INC. (US) 2022-04-21 WO disclosed
WO-2022081807-A1 SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER THE BROAD INSTITUTE, INC. (US) 2022-04-21 WO disclosed
EP-2301995-A1 Polycarbonate resin composition containing triazine compound and molded article using the same Fujifilm Corporation (JP) 2011-03-30 EP disclosed
US-20090022824-A1 Pesticidal formulations AKHIL TECHNOLOGIES PTY LTD (AU) 2009-01-22 US disclosed
US-20080125531-A1 Polymerizable Composition, Thermoplastic Resin Composition, Crosslinked Resin, And Crosslinked Resin Composite Materials ZEON COROPRATION (JP) 2008-05-29 US disclosed
WO-2006116817-A1 PESTICIDAL FORMULATIONS AKHIL TECHNOLOGIES PTY LTD (AU) 2006-11-09 WO disclosed
EP-1589054-A1 POLYMERIZABLE COMPOSITION, THERMOPLASTIC RESIN COMPOSITION, CROSSLINKED RESIN, AND CROSSLINKED RESIN COMPOSITE MATERIALS Zeon Corporation (JP) 2005-10-26 EP disclosed
EP-0446722-A1 Novel hydroxylated phenoxy compounds and process for their preparation Bromine Compounds Ltd. (IL) 1991-09-18 EP disclosed
US-4101323-A Radiation-sensitive copying composition HOECHST AKTIENGESELLSCHAFT (DE) 1978-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090022824-A1 Pesticidal formulations DDT, ACHE, PTMS LTA4H 2374/4885NR1H2 3882/4885BAX 52/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.