Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | ESRRG | P62508 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825065 | 0.86 | ESR1 (0.52) | ESR1ESR2ARPGRMEN1 | |
| SCHEMBL10749041 | 0.86 | ESR1 (0.52) | ESR1ESR2ARPGRMEN1 | |
| SCHEMBL24691090 | 0.81 | HTR2A (0.47) | ESR1ARHPGDTSHRSLC6A4 | |
| SCHEMBL9860042 | 0.80 | SLC6A4 (0.47) | ESR1HPGDTSHRSLC6A2SLC6A4 | |
| SCHEMBL2988842 | 0.80 | ALDH1A1 (0.49) | CYP3A4HPGDTSHRSLC6A4ALDH1A1 | |
| SCHEMBL8494426 | 0.80 | ALDH1A1 (0.49) | CYP3A4HPGDTSHRSLC6A4ALDH1A1 | |
| SCHEMBL5082815 | 0.79 | LTA4H (0.52) | ESR2ARHPGDTSHRHSD17B10 | |
| SCHEMBL29363720 | 0.79 | ALDH1A1 (0.56) | ESR1CYP3A4HPGDTSHRALDH1A1 | |
| SCHEMBL1857666 | 0.79 | ALDH1A1 (0.56) | ESR1CYP3A4HPGDTSHRALDH1A1 | |
| Phosphoric Acid SCHEMBL6261693 | 0.78 | MAPT (0.40) | ESR1HPGDTSHRSLC6A4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446722-A1 | Novel hydroxylated phenoxy compounds and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | disclosed |