SCHEMBL9853741

SCHEMBL9853741

Sc1cccc2ncsc12

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.45
HSD17B10 Q99714 1/20 0.45
PSMD14 O00487 1/20 0.33
COPS5 Q92905 1/20 0.33
PRMT5 O14744 1/20 0.33
OPRM1 P35372 1/20 0.30
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29806829 0.74 ALDH1A1 (0.45) ALDH1A1HSD17B10PRMT5
SCHEMBL6972765 0.74 ALDH1A1 (0.45) ALDH1A1HSD17B10PRMT5OPRM1OPRL1
SCHEMBL928489 0.74 ALDH1A1 (0.45) ALDH1A1HSD17B10PRMT5
SCHEMBL115602 0.74 ALDH1A1 (0.45) ALDH1A1HSD17B10PRMT5OPRM1OPRL1
SCHEMBL2093035 0.74 ALDH1A1 (0.45) ALDH1A1HSD17B10PRMT5
SCHEMBL5562354 0.74 ALDH1A1 (0.45) ALDH1A1HSD17B10PRMT5OPRM1OPRL1
SCHEMBL659126 0.74 ALDH1A1 (0.45) ALDH1A1HSD17B10PRMT5OPRM1OPRL1
SCHEMBL288616 0.74 ALDH1A1 (0.45) ALDH1A1HSD17B10PRMT5OPRM1OPRL1
SCHEMBL115601 0.74 ALDH1A1 (0.45) ALDH1A1HSD17B10OPRM1OPRL1
SCHEMBL30081471 0.74 ALDH1A1 (0.45) ALDH1A1HSD17B10OPRM1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118389576-B Autophagy related protein ZmATG c and application of encoding gene thereof in regulation of heat resistance of plants 西北农林科技大学 2026-05-19 CN disclosed
CN-118389576-A Autophagy related protein ZmATG c and application of encoding gene thereof in regulation of heat resistance of plants 西北农林科技大学 2024-07-26 CN disclosed
US-11498930-B2 Pyrimidine-fused cyclic compound, preparation method therefor and application thereof Blueray Therapeutics (Shanghai) Co., Ltd (CN) 2022-11-15 US disclosed
CN-111057074-B Inhibitors of influenza virus replication and uses thereof 广东东阳光药业有限公司 2022-04-29 CN disclosed
US-20210053989-A1 PYRIMIDINE-FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SHANGHAI BLUERAY BIOPHARMA CO., LTD. (CN) 2021-02-25 US disclosed
CN-111057074-A Inhibitors of influenza virus replication and uses thereof 广东东阳光药业有限公司 2020-04-24 CN disclosed
EP-0451983-A2 Power transmission belt MITSUBOSHI BELTING LTD. (JP) 1991-10-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11498930-B2 Pyrimidine-fused cyclic compound, preparation method therefor and application thereof PTPN11, PPM1F, PTPRF ALDH1A1 3190/4885HSD17B10 3100/4885PSMD14 4114/4885
US-20210053989-A1 PYRIMIDINE-FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF PTPN11, PPM1F, PTPRF ALDH1A1 3190/4885HSD17B10 3100/4885PSMD14 4114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.