Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | AOC1 | P19801 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | TEK | Q02763 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9853811 | 0.93 | KDM4C (0.42) | KDM4CKDM4ESLC22A12ICAM1SELE | |
| SCHEMBL9853814 | 0.81 | KDM4C (0.39) | KDM4CKDM4ESLC22A12POLBGAA | |
| SCHEMBL9853794 | 0.79 | KDM4E (0.40) | KDM4CKDM4EPOLBGAA | |
| SCHEMBL5950358 | 0.77 | SLC6A2 (0.50) | SLC6A4SLC6A2KDM4EMAPK1SLC6A3 | |
| SCHEMBL9853585 | 0.76 | CYP3A4 (0.46) | KDM4EMAPK1POLBHTTRAD52 | |
| SCHEMBL27254979 | 0.75 | CYP19A1 (0.46) | KDM4CSLC6A4SLC6A2KDM4EMAPK1 | |
| SCHEMBL9853270 | 0.74 | KDM4E (0.51) | KDM4CKDM4EMAPK1HTTGAA | |
| SCHEMBL4374807 | 0.73 | PTGS1 (0.50) | KDM4CMAPK1GAAICAM1SELE | |
| SCHEMBL23012547 | 0.72 | PTGS1 (0.48) | KDM4CMAPK1HTT | |
| SCHEMBL8777062 | 0.72 | HRH1 (0.44) | SLC6A4SLC6A2KDM4EMAPK1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | claimed |
| EP-0405487-A1 | Phenoxypyridinamines and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | disclosed |