Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.35 |
| ▸ | TSPO | P30536 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853824 | 0.81 | KDM4C (0.38) | KDM4CICAM1SELEVCAM1SLC22A12 | |
| Oxalic Acid SCHEMBL9853811 | 0.81 | KDM4C (0.42) | KDM4CICAM1SELEVCAM1CXCL8 | |
| SCHEMBL9853794 | 0.79 | KDM4E (0.40) | KDM4CCXCL8TSPOOPRK1KDM4E | |
| SCHEMBL9853270 | 0.74 | KDM4E (0.51) | KDM4CKDM4EALDH1A1KMT2ATDP1 | |
| SCHEMBL29795188 | 0.74 | ALDH1A1 (0.39) | KDM4CTSPOOPRK1ALDH1A1KMT2A | |
| SCHEMBL9853795 | 0.71 | ALDH1A1 (0.57) | KDM4EALDH1A1KMT2ATDP1MEN1 | |
| Hydrochloric Acid SCHEMBL9853808 | 0.70 | ALDH1A1 (0.56) | KDM4EALDH1A1KMT2ATDP1MEN1 | |
| SCHEMBL9853585 | 0.68 | CYP3A4 (0.46) | KDM4EALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL4374807 | 0.68 | PTGS1 (0.50) | KDM4CICAM1SELEALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL9853816 | 0.66 | PTGS1 (0.49) | KDM4CICAM1SELEALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405487-A1 | Phenoxypyridinamines and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | disclosed |