Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853829 | 0.81 | LMNA (0.45) | ALDH1A1TDP1GAAPOLBMEN1 | |
| SCHEMBL9853824 | 0.79 | KDM4C (0.38) | KDM4EGAAKDM4CPOLB | |
| SCHEMBL9853814 | 0.79 | KDM4C (0.39) | KDM4EALDH1A1TDP1GLAGAA | |
| Oxalic Acid SCHEMBL9853811 | 0.79 | KDM4C (0.42) | KDM4EALDH1A1TDP1KDM4CCXCL8 | |
| SCHEMBL9853795 | 0.77 | ALDH1A1 (0.57) | KDM4EALDH1A1TDP1GLAGAA | |
| SCHEMBL9488096 | 0.77 | PTGS1 (0.50) | ALDH1A1KDM4CDGAT2TSPOOPRK1 | |
| Hydrochloric Acid SCHEMBL9853808 | 0.76 | ALDH1A1 (0.56) | KDM4EALDH1A1TDP1GLAGAA | |
| SCHEMBL18808055 | 0.76 | ALDH1A1 (0.54) | KDM4EALDH1A1TDP1GLAGAA | |
| SCHEMBL837233 | 0.73 | RIPK1 (0.51) | KDM4EALDH1A1TDP1GAAPOLB | |
| Hydrochloric Acid SCHEMBL29061400 | 0.73 | ALDH1A1 (0.46) | KDM4EALDH1A1GAAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | claimed |
| EP-0405487-A1 | Phenoxypyridinamines and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | disclosed |