SCHEMBL9853830

SCHEMBL9853830

CSc1ccc(OC(=O)OC(Cl)c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.43
MEN1 O00255 5/20 0.43
L3MBTL1 Q9Y468 3/20 0.40
ATM Q13315 2/20 0.40
NPY5R Q15761 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
GAA P10253 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
PKM P14618 1/20 0.37
AKR1C3 P42330 4/20 0.36
AKR1C2 P52895 4/20 0.36
AKR1C1 Q04828 1/20 0.35
RAB9A P51151 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8995660 0.85 ATM (0.45) KMT2AMEN1L3MBTL1ATMNPY5R
SCHEMBL2287443 0.80 AKR1C3 (0.37) KMT2AMEN1NPSR1LMNACYP1A2
SCHEMBL2291255 0.78 AKR1C3 (0.36) KMT2AMEN1NPSR1LMNACYP1A2
SCHEMBL10445962 0.77 ALDH1A1 (0.43) KMT2AMEN1ALDH1A1LMNACYP1A2
SCHEMBL18476480 0.76 ALDH1A1 (0.52) KMT2AALDH1A1LMNAGAAPKM
SCHEMBL984298 0.76 CYP2D6 (0.44) KMT2AL3MBTL1ALDH1A1LMNATDP1
SCHEMBL9351782 0.76 MEN1 (0.50) KMT2AMEN1NPSR1ALDH1A1LMNA
SCHEMBL20537070 0.74 KMT2A (0.46) KMT2AMEN1L3MBTL1NPSR1ALDH1A1
SCHEMBL16702786 0.72 ACACB (0.38) KMT2AMEN1NPSR1ALDH1A1LMNA
SCHEMBL10434505 0.72 AKR1C3 (0.36) KMT2AMEN1NPSR1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0406567-A2 Process for the production of sulfonium compounds and novel methylthiophenol derivatives MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1991-01-09 EP disclosed