Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL984298 | 0.86 | CYP2D6 (0.44) | L3MBTL1TDP1LMNAHPGDCYP2D6 | |
| SCHEMBL9853830 | 0.85 | KMT2A (0.43) | ATML3MBTL1TDP1NPY5RLMNA | |
| SCHEMBL18476480 | 0.83 | ALDH1A1 (0.52) | MGLLLMNAALDH1A1GAAKMT2A | |
| SCHEMBL4492405 | 0.79 | ALOX15 (0.43) | ATML3MBTL1TDP1NPY5RLMNA | |
| SCHEMBL29001732 | 0.79 | ATM (0.40) | ATML3MBTL1TDP1LMNAHPGD | |
| SCHEMBL1096587 | 0.78 | CYP2D6 (0.44) | L3MBTL1TDP1LMNAHPGDCYP2D6 | |
| SCHEMBL27840777 | 0.78 | CYP2D6 (0.44) | L3MBTL1TDP1LMNAHPGDCYP2D6 | |
| SCHEMBL8846903 | 0.78 | HCAR2 (0.53) | ATML3MBTL1MGLLNPY5RLMNA | |
| SCHEMBL8775046 | 0.76 | ALDH1A1 (0.41) | ATML3MBTL1TDP1HPGDALOX15 | |
| SCHEMBL825537 | 0.76 | CYP2D6 (0.48) | L3MBTL1TDP1LMNAHPGDCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559266-A | Iodinated esters | NYCOMED IMAGING AS (NO) | 1996-09-24 | — | — | US | disclosed |
| US-5416223-A | Iodinated esters | NYCOMED IMAGING AS (NO) | 1995-05-16 | — | — | US | disclosed |
| US-5370861-A | Iodinated esters contrast medium and use | NYCOMED IMAGING AS (NO) | 1994-12-06 | — | — | US | disclosed |
| EP-0452377-B1 | IODINATED ESTERS | NYCOMED IMAGING AS (NO) | 1994-09-21 | — | — | EP | disclosed |
| EP-0452377-A1 | IODINATED ESTERS. | HOLMES MICHAEL JOHN (GB) | 1991-10-23 | — | — | EP | disclosed |
| WO-1990007491-A1 | IODINATED ESTERS | NYCOMED AS (NO) | 1990-07-12 | — | — | WO | disclosed |