Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.79 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.63 |
| ▸ | HTR1A | P08908 | 13/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 12/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 10/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 11/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13661568 | 0.87 | GAA (0.61) | GAATMEM97SIGMAR1HTR1AADRA1B | |
| SCHEMBL10487109 | 0.82 | GAA (0.56) | GAATMEM97SIGMAR1HTR1AADRA1B | |
| SCHEMBL10487078 | 0.82 | GAA (0.56) | GAATMEM97SIGMAR1HTR1AADRA1B | |
| SCHEMBL9426366 | 0.80 | GAA (0.53) | GAATMEM97SIGMAR1HTR1AADRA1B | |
| SCHEMBL13381099 | 0.75 | PABPC1 (0.59) | GAATMEM97SIGMAR1HTR1AADRA1B | |
| SCHEMBL18885118 | 0.75 | PABPC1 (0.59) | GAATMEM97SIGMAR1HTR1AADRA1B | |
| SCHEMBL714617 | 0.73 | PABPC1 (0.53) | GAATMEM97SIGMAR1HTR1AADRA1B | |
| SCHEMBL1487109 | 0.73 | PABPC1 (0.53) | GAATMEM97SIGMAR1HTR1AADRA1B | |
| SCHEMBL8192982 | 0.73 | PABPC1 (0.53) | GAATMEM97SIGMAR1HTR1AADRA1B | |
| SCHEMBL8325616 | 0.73 | PABPC1 (0.53) | GAATMEM97SIGMAR1HTR1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413223-A2 | N-heterocyclomethyl-spiroheterocyclic compounds and fungicide containing them | BASF Aktiengesellschaft (DE) | 1991-02-20 | — | — | EP | disclosed |