Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 14/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 13/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 12/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 12/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9426648 | 0.87 | GAA (0.42) | GAAHTR1ATMEM97SIGMAR1ADRA1B | |
| SCHEMBL8996692 | 0.82 | GAA (0.39) | GAAHTR1ATMEM97SIGMAR1ADRA1B | |
| SCHEMBL9426913 | 0.80 | GAA (0.41) | GAAHTR1ATMEM97SIGMAR1ADRA1B | |
| SCHEMBL9853850 | 0.80 | GAA (0.79) | GAAHTR1ATMEM97SIGMAR1ADRA1B | |
| SCHEMBL10487109 | 0.78 | GAA (0.56) | GAAHTR1ATMEM97SIGMAR1ADRA1B | |
| SCHEMBL10487078 | 0.78 | GAA (0.56) | GAAHTR1ATMEM97SIGMAR1ADRA1B | |
| SCHEMBL8996630 | 0.77 | PABPC1 (0.34) | GAAPABPC1CTDSP1 | |
| SCHEMBL13661568 | 0.75 | GAA (0.61) | GAAHTR1ATMEM97SIGMAR1ADRA1B | |
| SCHEMBL9003941 | 0.72 | GAA (0.39) | GAAHTR1ATMEM97SIGMAR1ADRA1B | |
| SCHEMBL13823649 | 0.71 | ADRA1A (0.32) | ADRA1APABPC1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5376660-A | An aminomethyl-1,4-dioxaspiro(4,5)decanes pesticides or fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-12-27 | — | — | US | claimed |