SCHEMBL98539

SCHEMBL98539

C=C(C)C(=O)NCCC(O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.38
ANPEP P15144 4/20 0.35
RNPEP Q9H4A4 3/20 0.35
DNPEP Q9ULA0 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.33
RAB9A P51151 2/20 0.33
ALDH1A1 P00352 2/20 0.33
GAA P10253 1/20 0.33
NPC1 O15118 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MTNR1A P48039 1/20 0.32
MTNR1B P49286 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA4 P43681 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28346305 0.88 KDM4E (0.37) TGFBR1ALDH1A1GAAMEN1KMT2A
SCHEMBL28345627 0.86 KDM4E (0.40) TGFBR1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL157717 0.85 ALDH1A1 (0.45) TGFBR1ANPEPRNPEPDNPEPSMN1; SMN2
SCHEMBL7523073 0.83 ANPEP (0.33) TGFBR1ANPEPRNPEPDNPEPSMN1; SMN2
SCHEMBL9400098 0.83 TGFBR1 (0.37) TGFBR1ANPEPRNPEPDNPEP
SCHEMBL3235398 0.83 ANPEP (0.52) TGFBR1ANPEPRNPEPDNPEPSMN1; SMN2
SCHEMBL7757017 0.82 TGFBR1 (0.35) TGFBR1ANPEPRNPEPDNPEPSMN1; SMN2
SCHEMBL18141154 0.82 TGFBR1 (0.43) TGFBR1ANPEPRNPEPDNPEPSMN1; SMN2
SCHEMBL316224 0.81 TGFBR1 (0.41) TGFBR1SMN1; SMN2RAB9AALDH1A1NPC1
SCHEMBL7129431 0.81 ANPEP (0.42) TGFBR1ANPEPRNPEPDNPEPSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3817764-B1 BIOPHARMACEUTICAL AGENTS FOR USE IN REDUCING LIPID CONTENT IN CELLS UNIV JOHANNESBURG WITWATERSRAND (ZA) 2024-04-17 EP claimed
EP-2774625-B1 POLYMER-TYPE FLUORESCENT MOLECULE PROBE MAEDA HIROSHI (JP) 2017-04-12 EP claimed
EP-1833526-B1 POLYMERS OF FLUORINATED MONOMERS AND HYDROCARBON MONOMERS ABBOTT CARDIOVASCULAR SYSTEMS (US) 2011-11-09 EP claimed
EP-1173878-B1 PROBES FOR A GAS PHASE ION SPECTROMETER BIO RAD LABORATORIES (US) 2011-04-06 EP claimed
EP-1534347-B1 CONJUGATES OF N-HYDROXYPROPYMETHACRYLAMIDE-METHACRYLATE COPOLYMER WITH NUCLIDE ACTIVATION AGENT AND/OR ANTI-CANCER COMPOUNDS PSIMEI PHARMACEUTICALS PLC (GB) 2009-12-02 EP claimed
EP-4025617-A1 HYDROXYALKYLAMIDE FUNCTIONALIZED ACRYLIC POLYMERS AND PROCESS FOR MANUFACTURING THEM Poliresin S.r.l. (IT) 2022-07-13 EP disclosed
CN-107528067-B Conductive slurry for lithium ion battery positive electrode and composite material slurry for lithium ion battery positive electrode 关西涂料株式会社 2021-07-20 CN disclosed
WO-2021044188-A1 HYDROXYALKYLAMIDE FUNCTIONALIZED ACRYLIC POLYMERS AND PROCESS FOR MANUFACTURING THEM POLIRESIN S.R.L. (IT) 2021-03-11 WO disclosed
CN-106463386-B Method for polishing silicon wafer, polishing composition, and polishing composition set 福吉米株式会社 2020-12-01 CN disclosed
CN-106456830-B (meth) acrylamide polymers for contact lenses and intraocular lenses 宾视研发公司 2020-11-03 CN disclosed
CN-111040731-A Composition for polishing silicon wafer 福吉米株式会社 2020-04-21 CN disclosed
CN-106981662-B Conductive slurry for lithium ion battery positive electrode and composite material slurry for lithium ion battery positive electrode 关西涂料株式会社 2019-12-20 CN disclosed
EP-0435633-B1 Electrically conductive layer for electrical devices XEROX CORP (US) 1996-09-11 EP disclosed
EP-0435634-B1 Conductive and blocking layers for electrophotographic imaging members XEROX CORP (US) 1995-11-02 EP disclosed
US-5063128-A Forming a semitransparent conductive layer of particles having acidic surfaces and a polymer; xerography; humidity resistance; durability XEROX CORPORATION (US) 1991-11-05 US disclosed
US-5063125-A For electrographic imaging XEROX CORPORATION (US) 1991-11-05 US disclosed
EP-0435634-A2 Conductive and blocking layers for electrophotographic imaging members XEROX CORPORATION (US) 1991-07-03 EP disclosed
EP-0435633-A2 Electrically conductive layer for electrical devices XEROX CORPORATION (US) 1991-07-03 EP disclosed
EP-0435635-A2 Electrically conductive layer for electrical devices XEROX CORPORATION (US) 1991-07-03 EP disclosed
US-4988597-A MULTILAYER ELECTROGRAPHY IMAGING PROCESS AND ELEMENT, A PHOTOCONDUCTIVE LAYER, AN ELECTROCONDUCTIVE LAYER OF A PARTIALLY CRO SSLINKED POLYMER OF ACRYLAMIDOGLYCOLATE ALKYL ETHER XEROX CORPORATION (US) 1991-01-29 US disclosed