Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.80 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.71 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.64 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.64 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | QPCT | Q16769 | 1/20 | 0.61 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.61 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5478998 | 0.87 | CYP19A1 (0.73) | CYP19A1TBXAS1CYP11B1CYP11B2AGTR2 | |
| SCHEMBL24247782 | 0.85 | CYP19A1 (0.70) | CYP19A1TBXAS1CYP11B1CYP11B2AGTR2 | |
| SCHEMBL20646872 | 0.83 | CYP19A1 (0.68) | CYP19A1TBXAS1CYP11B1CYP11B2AGTR2 | |
| SCHEMBL10531228 | 0.83 | TBXAS1 (1.00) | CYP19A1TBXAS1 | |
| SCHEMBL394308 | 0.82 | CYP11B1 (0.83) | CYP19A1TBXAS1CYP11B1CYP11B2CYP1A2 | |
| Hydrochloric Acid SCHEMBL10671782 | 0.82 | TBXAS1 (0.97) | CYP19A1TBXAS1 | |
| SCHEMBL11377854 | 0.82 | CYP19A1 (0.73) | CYP19A1TBXAS1 | |
| SCHEMBL4492287 | 0.81 | CYP19A1 (0.75) | CYP19A1TBXAS1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL27993981 | 0.81 | CYP19A1 (0.65) | CYP19A1TBXAS1CYP11B1CYP11B2AGTR2 | |
| SCHEMBL29865385 | 0.81 | HTT (0.65) | CYP19A1POLBCYP2D6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2743256-B1 | CYCLOPROPANEAMINE COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2018-06-27 | — | — | EP | disclosed |
| US-9682925-B2 | Cyclopropaneamine compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-06-20 | — | — | US | disclosed |
| CN-103842332-B | Cyclopropylamine compound | 武田药品工业株式会社 | 2016-08-17 | — | — | CN | disclosed |
| US-20160130215-A1 | CYCLOPROPANEAMINE COMPOUND | TAKEDA PHARMACEUTICAL (JP) | 2016-05-12 | — | — | US | disclosed |
| US-9278931-B2 | Cyclopropaneamine compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-03-08 | — | — | US | disclosed |
| US-20140228405-A1 | CYCLOPROPANEAMINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-08-14 | — | — | US | disclosed |
| EP-2743256-A1 | CYCLOPROPANEAMINE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2014-06-18 | — | — | EP | disclosed |
| CN-103842332-A | Cyclopropaneamine compound | TAKAEDA CHEMICAL IND LTD | 2014-06-04 | — | — | CN | disclosed |
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160130215-A1 | CYCLOPROPANEAMINE COMPOUND | KDM1A, KDM1B, KDM3A | CYP19A1 170/4885TBXAS1 2264/4885CYP11B1 226/4885 |
| US-20140228405-A1 | CYCLOPROPANEAMINE COMPOUND | KDM1A, KDM1B, KDM3A | CYP19A1 170/4885TBXAS1 2264/4885CYP11B1 226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.