Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PTAFR | P25105 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854052 | 0.86 | PTAFR (0.47) | POLBMAPTNPSR1TBXAS1PTAFR | |
| SCHEMBL9854109 | 0.85 | PTAFR (0.52) | MAPTPTAFR | |
| SCHEMBL9854038 | 0.84 | PTAFR (0.54) | TBXAS1PTAFR | |
| SCHEMBL9853975 | 0.82 | PTAFR (0.54) | MAPTPTAFR | |
| SCHEMBL9854014 | 0.80 | PTAFR (0.59) | TBXAS1PTAFR | |
| SCHEMBL9853969 | 0.80 | TBXAS1 (0.51) | POLBMAPTNPSR1TBXAS1PTAFR | |
| SCHEMBL9854016 | 0.79 | PTAFR (0.49) | TBXAS1PTAFR | |
| SCHEMBL9854003 | 0.79 | PTAFR (0.51) | POLBTBXAS1PTAFRKMT2A | |
| SCHEMBL9854108 | 0.79 | PTAFR (0.56) | TBXAS1PTAFR | |
| SCHEMBL9853930 | 0.79 | PTAFR (0.64) | TBXAS1PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |