Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 4/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5018743 | 0.87 | PTGS1 (0.55) | ATML3MBTL1SRD5A2PTGS1PTGS2 | |
| SCHEMBL21064585 | 0.83 | PTGS1 (0.57) | PTGS1PTGS2CXCR1CXCR2LMNA | |
| SCHEMBL6072390 | 0.82 | ATM (0.57) | ATMTDP1L3MBTL1SRD5A2PTGS1 | |
| SCHEMBL765921 | 0.82 | FOLH1 (0.61) | — | |
| SCHEMBL27959311 | 0.81 | PTGS1 (0.60) | PTGS1PTGS2CXCR1CXCR2LMNA | |
| SCHEMBL452233 | 0.81 | PTGS1 (0.60) | PTGS1PTGS2CXCR1CXCR2LMNA | |
| SCHEMBL10483031 | 0.80 | L3MBTL1 (0.47) | ATMTDP1L3MBTL1CA1CA2 | |
| SCHEMBL21887389 | 0.79 | L3MBTL1 (0.53) | ATMTDP1L3MBTL1CA1CA2 | |
| SCHEMBL110317 | 0.79 | SRD5A2 (0.74) | ATMTDP1L3MBTL1CA1CA2 | |
| SCHEMBL8792890 | 0.79 | MRGPRX4 (0.52) | PTGS1PTGS2CXCR1CXCR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |