Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GLI1 | P08151 | 3/20 | 0.45 |
| ▸ | GLI2 | P10070 | 3/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854090 | 0.80 | ATM (0.52) | L3MBTL1ATMTDP1SRD5A2MAPT | |
| SCHEMBL5018743 | 0.80 | PTGS1 (0.55) | L3MBTL1ATMSRD5A2PTGS1CXCR1 | |
| SCHEMBL6072390 | 0.78 | ATM (0.57) | L3MBTL1ATMTDP1SRD5A2MAPT | |
| SCHEMBL10483032 | 0.74 | PTGS1 (0.45) | L3MBTL1ATMTDP1GLI1GLI2 | |
| Ketoprofen SCHEMBL20969451 | 0.74 | PTGS1 (0.74) | GLI1GLI2MAPTPTGS1CXCR1 | |
| Ketoprofen SCHEMBL572766 | 0.74 | PTGS1 (0.74) | GLI1GLI2MAPTPTGS1CXCR1 | |
| SCHEMBL664336 | 0.73 | FFAR1 (0.61) | PTGS1CXCR1CXCR2PTGS2ALDH1A1 | |
| SCHEMBL21064585 | 0.73 | PTGS1 (0.57) | PTGS1CXCR1CXCR2PTGS2SMN1; SMN2 | |
| SCHEMBL11138168 | 0.72 | ALDH1A1 (0.71) | L3MBTL1ATMSRD5A2SMN1; SMN2ALDH1A1 | |
| Acetophenone SCHEMBL22033274 | 0.72 | LMNA (0.61) | L3MBTL1MAPTPTGS1CXCR1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1203373-A | — | — | None | — | — | JP | disclosed |
| JP-H01203373-A | DERIVATIVE OF THIAZOLIDINE-4-CARBOXYLIC ACID HAVING PHARMACOLOGICAL ACTIVITY | ZAMBON GROUP SPA | 1989-08-16 | — | — | JP | disclosed |