Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2652913 | 0.78 | MAPK1 (0.46) | SQORMAPK1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL30777434 | 0.78 | CD274 (0.45) | SQORMAPK1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL588693 | 0.78 | CD274 (0.45) | SQORMAPK1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL29967703 | 0.78 | MAPK1 (0.46) | SQORMAPK1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL2569037 | 0.78 | ALDH1A1 (0.44) | SQORMAPK1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL16122421 | 0.76 | ALDH1A1 (0.42) | SQORMAPK1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL28871241 | 0.75 | ALDH1A1 (0.43) | SQORMAPK1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL421377 | 0.75 | ALDH1A1 (0.41) | SQORMAPK1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL4958212 | 0.74 | ALDH1A1 (0.53) | SQORMAPK1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL16122425 | 0.73 | ADORA1 (0.51) | SQORMAPK1L3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426021-A1 | Condensed imidazole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |