Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27407041 | 0.85 | ABCG2 (0.38) | ALDH1A1CYP1A2CYP3A4HSD17B10HPGD | |
| SCHEMBL11108383 | 0.76 | EGFR (0.45) | ALDH1A1HTT | |
| SCHEMBL17120715 | 0.73 | ESR2 (0.59) | ALDH1A1CYP1A2CYP3A4HSD17B10HPGD | |
| SCHEMBL5584219 | 0.71 | CHRM5 (0.38) | ALDH1A1CYP1A2CYP3A4HPGDHTT | |
| SCHEMBL9854331 | 0.69 | CYP1A2 (0.52) | ALDH1A1CYP1A2CYP3A4HSD17B10HPGD | |
| SCHEMBL7447420 | 0.69 | AXL (0.42) | ALDH1A1CYP1A2CYP3A4HSD17B10HPGD | |
| SCHEMBL4359377 | 0.68 | ESR2 (0.66) | ALDH1A1CYP1A2CYP3A4HSD17B10HPGD | |
| SCHEMBL31410710 | 0.67 | ESR2 (0.76) | ALDH1A1CYP1A2CYP3A4HSD17B10HPGD | |
| SCHEMBL4949949 | 0.67 | ESR2 (0.51) | ALDH1A1CYP1A2CYP3A4HSD17B10ESR2 | |
| SCHEMBL16484546 | 0.67 | ESR2 (0.59) | ALDH1A1CYP1A2CYP3A4HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426021-A1 | Condensed imidazole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |