Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6191221 | 0.79 | HTT (0.45) | HPGDALDH1A1HTTSMN1; SMN2NPC1 | |
| SCHEMBL3783787 | 0.76 | ALDH1A1 (0.40) | HPGDALDH1A1HTTSMN1; SMN2NPC1 | |
| SCHEMBL21614128 | 0.75 | ALDH1A1 (0.39) | HPGDALDH1A1HTTSMN1; SMN2NPC1 | |
| SCHEMBL12125020 | 0.73 | HPGD (0.43) | HPGDALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL16580958 | 0.73 | HPGD (0.40) | HPGDALDH1A1HTTSMN1; SMN2NPC1 | |
| SCHEMBL5200518 | 0.71 | KCNMA1 (0.47) | HPGDALDH1A1HTTSMN1; SMN2NPC1 | |
| SCHEMBL9854328 | 0.71 | ALDH1A1 (0.44) | HPGDALDH1A1HTTCYP1A2CYP2D6 | |
| SCHEMBL1230919 | 0.71 | PTK2 (0.50) | ALDH1A1HTTJAK2JAK3 | |
| SCHEMBL14068342 | 0.70 | ALDH1A1 (0.35) | HPGDALDH1A1HTTSMN1; SMN2NPC1 | |
| SCHEMBL15060539 | 0.70 | PDE4B (0.35) | JAK2JAK3KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007513098-A | — | — | 2007-05-24 | — | — | JP | claimed |
| EP-1697312-A2 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | Leo Pharma A/S (DK) | 2006-09-06 | — | — | EP | claimed |
| WO-2005054179-A2 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | LEO PHARMA A/S (DK) | 2005-06-16 | — | — | WO | claimed |